Welcome!

API Journal Authors: Liz McMillan, Flint Brenton, Rishi Bhargava, Pat Romanski, Elizabeth White

News Feed Item

Michael J. Fox Foundation Surpasses $50-Million Brin Wojcicki Challenge

— $53 million matched, positioning Foundation for continued impact; opportunity and need persist in challenged research funding environment

NEW YORK, Feb. 27, 2013 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation for Parkinson's Research (MJFF) announced that with the help of the Parkinson's community, it has completed and surpassed the $50-million Brin Wojcicki Challenge. Longtime Foundation supporters Sergey Brin and Anne Wojcicki have matched more than $53 million in capacity-building gifts received by MJFF from January 1, 2011, to December 31, 2012.

Mr. Brin and Ms. Wojcicki, the Foundation's largest donors for several years running, spearheaded the Challenge to spur donors at every level to give, renew or increase giving to MJFF. Because of the enthusiasm and generosity of the Foundation's community of donors, Challenge-eligible giving exceeded the original goal by about $3 million — additional dollars that Mr. Brin and Ms. Wojcicki have agreed to match.

"Anne and Sergey's friendship to our Foundation and to Parkinson's patients worldwide is awe-inspiring," said Michael J. Fox. "As if a $50-million match weren't tremendous in its own right, they've gone above and beyond their initial commitment to match the $3 million extra ponied up by our incredible supporters. There's no doubt the Challenge has made our community stronger and more vibrant in its passionate pursuit of a cure."

Over the course of two years, the Challenge brought thousands of new contributors to MJFF. It also helped the Foundation reactivate relationships with thousands of supporters who had given prior to 2010, and motivated over 4,000 to stretch their giving in order to double the impact of their generosity.

Mr. Brin is co-founder of Google. Ms. Wojcicki is co-founder of 23andMe, a personal genetics company. With the completion of the Challenge, their personal giving to MJFF totals more than $157.5 million since 2004.

An opportune moment and an urgent need

Mr. Brin and Ms. Wojcicki chose an opportune moment in Parkinson's drug development to launch the Challenge. MJFF and most of its research partners believe that the pipeline of new Parkinson's treatments is as robust as it has been in decades, if not ever. Understanding of the factors underlying disease onset and progression is increasing, and insights from genetics are opening new avenues for therapeutic development. In the midst of this promising activity, government and commercial sources of research funding continue to dry up. Especially as more research approaches the clinic, where costs rise steeply, there has never been a more important time or a greater need for the Parkinson's community to work together to ensure funding sufficient to keep the most promising projects moving forward.

At the outset of 2013, MJFF remains focused on:

  • The search for a disease-modifying treatment. This spring, results are expected from Ceregene, Inc.'s most recent MJFF-supported Phase 2 clinical trial of neurturin, a trophic factor that could help restore dopamine neurons in the Parkinson's brain. As Parkinson's genetics continues to revolutionize the field, MJFF is growing its initiatives focused on alpha-synuclein and LRRK2, the two most important genetic targets in PD. And in coming months the Foundation's landmark biomarker study, Parkinson's Progression Markers Initiative (ppmi-info.org), will complete collection of baseline data (all of which has been made available to the research community at large in real time) and launch a new arm to study people at increased risk for the disease.
  • Looking beyond the dopamine system. Today researchers understand that Parkinson's involves a constellation of symptoms that go well beyond dopamine signaling. MJFF-enabled partnerships with Bristol Myers Squibb, Sanofi, Addex and other major pharmaceutical firms are pushing new classes of symptomatic therapies, as well as treatments for cognition and dyskinesia, closer than ever to the clinic.
  • Increasing the flow of willing volunteers for clinical research through Fox Trial Finder. Fox Trial Finder (foxtrialfinder.org) has registered more than 14,000 patient and control volunteers who want to be matched to the best trials for them. In 2013 the site comes online in five more European countries and aims to attain 30,000 registered volunteers by year-end.

"Our Foundation's promise to Parkinson's patients is to work urgently to identify and fund the projects closest or most critical to practical therapeutic relevance," said Todd Sherer, Ph.D., CEO of MJFF. "We're grateful to our Challenge participants and our entire community of supporters for helping us continue to fulfill that promise."

About The Michael J. Fox Foundation for Parkinson's Research
As the world's largest private funder of Parkinson's research, The Michael J. Fox Foundation is dedicated to accelerating a cure for Parkinson's disease and improved therapies for those living with the condition today. The Foundation pursues its goals through an aggressively funded, highly targeted research program coupled with active global engagement of scientists, Parkinson's patients, business leaders, clinical trial participants, donors and volunteers.  In addition to funding more than $300 million in research to date, the Foundation has fundamentally altered the trajectory of progress toward a cure. Operating at the hub of worldwide Parkinson's research, the Foundation forges groundbreaking collaborations with industry leaders, academic scientists and government research funders; increases the flow of participants into Parkinson's disease clinical trials with its online tool, Fox Trial Finder; promotes Parkinson's awareness through high-profile advocacy, events and outreach; and coordinates the grassroots involvement of thousands of Team Fox members around the world.

For more information, visit us at:
Web site: michaeljfox.org 
Facebook: facebook.com/michaeljfoxfoundation 
LinkedIn: bit.ly/mjffPDOR 
Twitter: @MichaelJFoxOrg

SOURCE The Michael J. Fox Foundation for Parkinson's Research

More Stories By PR Newswire

Copyright © 2007 PR Newswire. All rights reserved. Republication or redistribution of PRNewswire content is expressly prohibited without the prior written consent of PRNewswire. PRNewswire shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.

@ThingsExpo Stories
The Jevons Paradox suggests that when technological advances increase efficiency of a resource, it results in an overall increase in consumption. Writing on the increased use of coal as a result of technological improvements, 19th-century economist William Stanley Jevons found that these improvements led to the development of new ways to utilize coal. In his session at 19th Cloud Expo, Mark Thiele, Chief Strategy Officer for Apcera, will compare the Jevons Paradox to modern-day enterprise IT, e...
Complete Internet of Things (IoT) embedded device security is not just about the device but involves the entire product’s identity, data and control integrity, and services traversing the cloud. A device can no longer be looked at as an island; it is a part of a system. In fact, given the cross-domain interactions enabled by IoT it could be a part of many systems. Also, depending on where the device is deployed, for example, in the office building versus a factory floor or oil field, security ha...
SYS-CON Events announced today that Bsquare has been named “Silver Sponsor” of SYS-CON's @ThingsExpo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. For more than two decades, Bsquare has helped its customers extract business value from a broad array of physical assets by making them intelligent, connecting them, and using the data they generate to optimize business processes.
Identity is in everything and customers are looking to their providers to ensure the security of their identities, transactions and data. With the increased reliance on cloud-based services, service providers must build security and trust into their offerings, adding value to customers and improving the user experience. Making identity, security and privacy easy for customers provides a unique advantage over the competition.
There are several IoTs: the Industrial Internet, Consumer Wearables, Wearables and Healthcare, Supply Chains, and the movement toward Smart Grids, Cities, Regions, and Nations. There are competing communications standards every step of the way, a bewildering array of sensors and devices, and an entire world of competing data analytics platforms. To some this appears to be chaos. In this power panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, Bradley Holt, Developer Advocate a...
If you’re responsible for an application that depends on the data or functionality of various IoT endpoints – either sensors or devices – your brand reputation depends on the security, reliability, and compliance of its many integrated parts. If your application fails to deliver the expected business results, your customers and partners won't care if that failure stems from the code you developed or from a component that you integrated. What can you do to ensure that the endpoints work as expect...
So, you bought into the current machine learning craze and went on to collect millions/billions of records from this promising new data source. Now, what do you do with them? Too often, the abundance of data quickly turns into an abundance of problems. How do you extract that "magic essence" from your data without falling into the common pitfalls? In her session at @ThingsExpo, Natalia Ponomareva, Software Engineer at Google, provided tips on how to be successful in large scale machine learning...
In his general session at 18th Cloud Expo, Lee Atchison, Principal Cloud Architect and Advocate at New Relic, discussed cloud as a ‘better data center’ and how it adds new capacity (faster) and improves application availability (redundancy). The cloud is a ‘Dynamic Tool for Dynamic Apps’ and resource allocation is an integral part of your application architecture, so use only the resources you need and allocate /de-allocate resources on the fly.
If you had a chance to enter on the ground level of the largest e-commerce market in the world – would you? China is the world’s most populated country with the second largest economy and the world’s fastest growing market. It is estimated that by 2018 the Chinese market will be reaching over $30 billion in gaming revenue alone. Admittedly for a foreign company, doing business in China can be challenging. Often changing laws, administrative regulations and the often inscrutable Chinese Interne...
Enterprise IT has been in the era of Hybrid Cloud for some time now. But it seems most conversations about Hybrid are focused on integrating AWS, Microsoft Azure, or Google ECM into existing on-premises systems. Where is all the Private Cloud? What do technology providers need to do to make their offerings more compelling? How should enterprise IT executives and buyers define their focus, needs, and roadmap, and communicate that clearly to the providers?
SYS-CON Events announced today that Commvault, a global leader in enterprise data protection and information management, has been named “Bronze Sponsor” of SYS-CON's 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Commvault is a leading provider of data protection and information management solutions, helping companies worldwide activate their data to drive more value and business insight and to transform moder...
The many IoT deployments around the world are busy integrating smart devices and sensors into their enterprise IT infrastructures. Yet all of this technology – and there are an amazing number of choices – is of no use without the software to gather, communicate, and analyze the new data flows. Without software, there is no IT. In this power panel at @ThingsExpo, moderated by Conference Chair Roger Strukhoff, panelists will look at the protocols that communicate data and the emerging data analy...
Digital innovation is the next big wave of business transformation based on digital technologies of which IoT and Big Data are key components, For example: Business boundary innovation is a challenge to excavate third-party business value using IoT and BigData, like Nest Business structure innovation may propose re-building business structure from scratch, as Uber does in the taxicab industry The social model innovation is also a big challenge to the new social architecture with the design fr...
Fifty billion connected devices and still no winning protocols standards. HTTP, WebSockets, MQTT, and CoAP seem to be leading in the IoT protocol race at the moment but many more protocols are getting introduced on a regular basis. Each protocol has its pros and cons depending on the nature of the communications. Does there really need to be only one protocol to rule them all? Of course not. In his session at @ThingsExpo, Chris Matthieu, co-founder and CTO of Octoblu, walk you through how Oct...
Is your aging software platform suffering from technical debt while the market changes and demands new solutions at a faster clip? It’s a bold move, but you might consider walking away from your core platform and starting fresh. ReadyTalk did exactly that. In his General Session at 19th Cloud Expo, Michael Chambliss, Head of Engineering at ReadyTalk, will discuss why and how ReadyTalk diverted from healthy revenue and over a decade of audio conferencing product development to start an innovati...
Data is an unusual currency; it is not restricted by the same transactional limitations as money or people. In fact, the more that you leverage your data across multiple business use cases, the more valuable it becomes to the organization. And the same can be said about the organization’s analytics. In his session at 19th Cloud Expo, Bill Schmarzo, CTO for the Big Data Practice at EMC, will introduce a methodology for capturing, enriching and sharing data (and analytics) across the organizati...
There is little doubt that Big Data solutions will have an increasing role in the Enterprise IT mainstream over time. Big Data at Cloud Expo - to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA - has announced its Call for Papers is open. Cloud computing is being adopted in one form or another by 94% of enterprises today. Tens of billions of new devices are being connected to The Internet of Things. And Big Data is driving this bus. An exponential increase is...
IoT is fundamentally transforming the auto industry, turning the vehicle into a hub for connected services, including safety, infotainment and usage-based insurance. Auto manufacturers – and businesses across all verticals – have built an entire ecosystem around the Connected Car, creating new customer touch points and revenue streams. In his session at @ThingsExpo, Macario Namie, Head of IoT Strategy at Cisco Jasper, will share real-world examples of how IoT transforms the car from a static p...
Internet of @ThingsExpo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with the 19th International Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world and ThingsExpo Silicon Valley Call for Papers is now open.
SYS-CON Events has announced today that Roger Strukhoff has been named conference chair of Cloud Expo and @ThingsExpo 2016 Silicon Valley. The 19th Cloud Expo and 6th @ThingsExpo will take place on November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. "The Internet of Things brings trillions of dollars of opportunity to developers and enterprise IT, no matter how you measure it," stated Roger Strukhoff. "More importantly, it leverages the power of devices and the Interne...